Science · 2003 · 201 citations · 0 references
Veterinary MedicineImmunologyInfectious DiseasesVaccine ImmunologyVaccinologyVirologyClinical Vaccine TrialsVaccinationVaccine Delivery SystemsVaccine DevelopmentVaccine EffectivenessVaccine PolicyComparative TestingHuman Subject TrialsOverall Vaccine EffectivenessPreventive Hiv VaccinesVaccine Candidate ScreeningVaccine Clinical Trial DesignVaccine Efficacy AssessmentVaccine Production
A new collaborative model of research is needed to increase resources, to prioritize the R (ii) to increase the pace, reduce the overlap, and more systematically explore the elements of and delivery systems for vaccines; (iii) to use common standards for the prompt comparative testing of vaccine candidates; (iv) to expand resources for manufacturing vaccine candidates to speed their use in human trials; and (v) to increase the capacity for international clinical trials and to focus this effort toward quickly measuring the effectiveness of vaccine protection as prototype vaccine candidates are identified.