Concepedia

Publication | Closed Access

TRC4149 a novel advanced glycation end product breaker improves hemodynamic status in diabetic spontaneously hypertensive rats.

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Citations

0

References

2008

Year

P Pathak, Richa Gupta, Aparna Chaudhari, Ajay Shiwalkar, Amita Dubey, A B Mandhare, Rakesh Gupta, Deepa Joshi, V Chauthaiwale
PubMed

Abstract

TRC4149, a novel AGE-breaker compound, by virtue of reducing AGE load preserved endothelial and cardiac function in diabetic SHR, a model that recapitulates the microvascular and cardiac dysfunction associated with hypertension along with long-term diabetes.