<scp>BD</scp>750, a benzothiazole derivative, inhibits <scp>T</scp> cell proliferation by affecting the <scp>JAK</scp>3/<scp>STAT</scp>5 signalling pathway

Abstract

These data indicate that BD750 inhibits IL-2-induced JAK3/STAT5-dependent T cell proliferation. BD750 has the potential to be used as a lead compound for the design and development of new immunosuppressants for preventing graft rejection and treating autoimmune diseases.