BMC Medicine · 2006 · 59 citations · 15 references
Veterinary MedicineInfectious Disease ControlInfectious DiseasesCommunicable Disease ControlEpidemiologyInfectious Disease EpidemiologyDisease SpreadInfectious Disease DynamicsOutbreak ControlOutbreak ManagementOutbreak PreventionTransmission DynamicsContagious Disease SpreadDisease Outbreak ModelingEpidemic Spread SimulationModeling Of Outbreak SpreadSevere Acute Respiratory SyndromeStochastic Epidemic ModelsStochastic SimulationTravel Activity Patterns
BACKGROUND: Much research in epidemiology has been focused on evaluating conventional methods of control strategies in the event of an epidemic or pandemic. Travel restrictions are often suggested as an efficient way to reduce the spread of a contagious disease that threatens public health, but few papers have studied in depth the effects of travel restrictions. In this study, we investigated what effect different levels of travel restrictions might have on the speed and geographical spread of an outbreak of a disease similar to severe acute respiratory syndrome (SARS). METHODS: We used a stochastic simulation model incorporating survey data of travel patterns between municipalities in Sweden collected over 3 years. We tested scenarios of travel restrictions in which travel over distances >50 km and 20 km would be banned, taking into account different levels of compliance. RESULTS: We found that a ban on journeys >50 km would drastically reduce the speed and geographical spread of outbreaks, even when compliance is < 100%. The result was found to be robust for different rates of intermunicipality transmission intensities. CONCLUSION: This study supports travel restrictions as an effective way to mitigate the effect of a future disease outbreak.
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Modelling disease outbreaks in realistic urban social networks
Stephen Eubank, Hasan Güçlü, V. S. Anil Kumar et al. · Nature · 2004 · 2.2K citations · Full text
Veterinary Medicine, Infectious Diseases, Urban Planning +14
Strategies for containing an emerging influenza pandemic in Southeast Asia
Neil M. Ferguson, Derek A. T. Cummings, Simon Cauchemez et al. · Nature · 2005 · 1.9K citations · Full text
Medicine, Infectious Disease Control, Infectious Diseases +14
Transmission Dynamics and Control of Severe Acute Respiratory Syndrome
Marc Lipsitch, Ted Cohen, Ben S. Cooper et al. · Science · 2003 · 1.6K citations · Full text
Veterinary Medicine, Infectious Disease Control, Infectious Diseases +17