PubMed · 1978 · 38 citations · 0 references
Life SciencesImmunologyInfectious DiseasesAllergyClinical ImmunologyHypersensitivityAllergic DiseaseCell-mediated ImmunityIge-mediated AllergyLymphocyte ActivationType I HypersensitivityViral InfectionsAdaptive Immune Responses To Viral InfectionCellular Immune Response To VirusesIge-mediated HypersensitivityIge-mediated MechanismsIge-mediated ResponsesImmunoglobulin E (Ige)Respiratory Viral InfectionsViral Respiratory Infections
Six non-atopic patients with respiratory infections to a variety of viruses demonstrated a consistent drop in IgE levels (35% to 87%) in the convalescent phase compared to the acute phase of infection, suggesting that the viral agent affects T lymphocytes to suppress and hence B lymphocytes to secrete IgE immunoglobulin.