Analysis of molecular aspects of Na+ and Ca2+ uptakes by embryonic cardiac cells in culture.

Abstract

Veratridinestimulates Na+ and Ca"+ influx in the embryonic cardiac cell in culture; it does not influence Na+, Rb+ (a substitute for K+), or Ca'+ efflux rates.Veratridine increases the initial rate of Na+ influx by a factor of 5 at 0.1 mM.Its half-maximum (KO.S,reratridine)) effect is observed at 22 PM.