POLYRIBOSOMES IN RAT TISSUES. I. A STUDY OF IN VIVO PATTERNS IN LIVER AND HEPATOMAS.

Abstract

Summary The polyribosome patterns of several hepatomas have been compared with that of liver. In contrast to liver the hepatomas are characterized by: (a) a relatively higher proportion of monomers and the lighter polyribosomes, (b) a lower and variable proportion of the heavier polyribosomes, (c) a polyribosome complement which, after release from the cell, sediments through 2.0 m sucrose without detergent treatment, and (d) a greater capacity to maintain their polyribosome pattern during fasting.