α<sub>1</sub>‐Adrenoceptor‐mediated depletion of phosphatidylinositol 4, 5‐bisphosphate inhibits activation of volume‐regulated anion channels in mouse ventricular myocytes - Concepedia

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α<sub>1</sub>‐Adrenoceptor‐mediated depletion of phosphatidylinositol 4, 5‐bisphosphate inhibits activation of volume‐regulated anion channels in mouse ventricular myocytes

DOI Full Paper Access

15

Citations

45

References

2010

Year

Kunihiko Ichishima, Shintaro Yamamoto, Takahiro Iwamoto, Tsuguhisa Ehara

British Journal of Pharmacology

Abstract

Our results indicate that the stimulation of alpha(1A)-adrenoceptors by PE inhibited the activation of cardiac VRAC current via PIP(3) depletion brought about by PLC-dependent reduction of membrane PIP(2) level.

References

	Year	Citations

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