Effect of <scp>PUVA</scp> therapy on melanocytes and keratinocytes in non‐segmental vitiligo: histopathological, immuno‐histochemical and ultrastructural study

Abstract

Vitiligo affects both melanocytes and keratinocytes causing degenerative changes. These changes were present in both the leucodermic and the apparently normal perilesional skin. PUVA increases the number of active epidermal melanocytes in the three tested areas and recovers the melanocyte and keratinocyte degeneration.