Age-related functional and structural retinal modifications in the Igf1−/− null mouse

Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r)

Jeh-Ping Liu, Julie C. Baker, Archlbald S. Perkins et al. · Cell · 1993 · 2.9K citations

Life Sciences, Developmental Biology, Genetics +16

Intrauterine Growth Retardation and Postnatal Growth Failure Associated with Deletion of the Insulin-Like Growth Factor I Gene

Katie A. Woods, Cecilia Camacho‐Hübner, Martin O. Savage et al. · New England Journal of Medicine · 1996 · 1.1K citations · Full text

Life Sciences, Endocrinology, Genetics +17

Retinal degeneration in the rd mouse is caused by a defect in the β subunit of rod cGMP-phosphodiesterase

Cathy Bowes, Tiansen Li, Michael Danciger et al. · Nature · 1990 · 858 citations

Medicine, Neuroscience, Ophthalmology +17

Igf1 gene disruption results in reduced brain size, CNS hypomyelination, and loss of hippocampal granule and striatal parvalbumin-containing neurons

Klaus D Beck, Lyn Powell-Braxtont, H. R. Widmer et al. · Neuron · 1995 · 636 citations

Life Sciences, Neurobiology, Neuroscience +10

Retinal organization in the retinal degeneration 10 (rd10) mutant mouse: A morphological and ERG study

Claudia Gargini, Eva Terzibasi Tozzini, Francesca Mazzoni et al. · The Journal of Comparative Neurology · 2006 · 518 citations · Full text

Medicine, Neuroscience, Ophthalmology +17