MedicineCardiologyInternal MedicineCardiac Nuclear MedicineClinical CardiologyNuclear CardiologyCardiac ArrhythmiasCardiovascular DiseaseCoronary Artery DiseaseCoronary Artery ImagingElectrocardiographyIschemic Heart DiseaseBeta-blocker Therapy ManagementCardiovascular AnomaliesCongenital Cardiac AnomaliesCongenital Coronary AnomaliesCongenital Coronary Artery AnomaliesCoronary Artery Anomaly DetectionCoronary Artery Anomaly ImagingExtracardiac Vascular Anomalies
A 41-year-old man with no relevant cardiac history presented for evaluation of episodic syncope. Electrocardiography showed sinus rhythm with right bundle-branch block and Q waves in leads II, III, and aVF. Subsequent exercise treadmill testing and technetium 99m sestamibi study revealed a reversible posterior defect. Coronary angiography later showed a right coronary artery that arose from the left coronary sinus--an anomaly that has been associated with angina, myocardial infarction, and sudden cardiac death. After being informed of the potential risks and options associated with this anomaly, the patient chose long-term beta-blocker medical therapy. At follow-up, this treatment appeared to have resolved his episodic syncope.
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Anomalies of the Coronary Arteries and their Clinical Significance
R. W. Alexander, George C. Griffith · Circulation · 1956 · 398 citations · Full text
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On Topaz, Eduardo DeMarchena, Emerson C. Perin et al. · International Journal of Cardiology · 1992 · 241 citations
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