Design and In Vivo Evaluation of An Oral Delivery System for Insulin

The development of stable protein formulations: a close look at protein aggregation, deamidation, and oxidation.

Jeffrey L. Cleland, Melissa Powell, S J Shire · PubMed · 1993 · 542 citations

Pharmacy, Biochemistry, Pharmaceutics +17

Receptor-binding region of insulin

Robin Püllen, D.G. Lindsay, S. P. Wood et al. · Nature · 1976 · 391 citations

Life Sciences, Endocrinology, Molecular Biology +12

Enteral Absorption of Insulin in Rats from Mucoadhesive Chitosan-Coated Liposomes

Hirofumi Takeuchi, Hiromitsu Yamamoto, Toshiyuki Niwa et al. · Pharmaceutical Research · 1996 · 388 citations · Full text

Pharmacy, Molecular Pharmaceutics, Pharmaceutics +14

Polymers with Thiol Groups: A New Generation of Mucoadhesive Polymers?

Andreas Bernkop‐Schnürch, Veronika Schwarz, Sonja Steininger · Pharmaceutical Research · 1999 · 337 citations

Natural Sciences, Materials Science, Pharmaceutics +16

Chitosan Capsules for Colon-Specific Drug Delivery: Improvement of Insulin Absorption from the Rat Colon

Hideyuki Tozaki, Junta Komoike, Chika Tada et al. · Journal of Pharmaceutical Sciences · 1997 · 315 citations

Pharmacy, Pharmaceutics, Pharmacology +15