Concepedia

Perivascular adipose tissue-derived relaxing factors: release by peptide agonists via proteinase-activated receptor-2 (PAR2) and non-PAR2 mechanisms

Y Li, Koichiro Mihara, Mahmoud Saifeddine, A Krawetz, DCW Lau, Hou‐wei Li, Hong Ding, MD Hollenberg

British Journal of Pharmacology · 2011 · 18 citations · 32 references

DOIFull text

Open access

Abstract

Distinct ADRFs that may modulate vascular tone in pathophysiological settings can be released from murine PVAT by both PAR2-dependent and PAR2-independent mechanisms.

References

32

Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation

Thienkhai Vu, David T. Hung, V I Wheaton et al. · Cell · 1991 · 3K citations

, , +15

Guide to Receptors and Channels (GRAC), 5th edition

S P H Alexander, Alistair Mathie, JA Peters · British Journal of Pharmacology · 2011 · 1.9K citations · Full text

Proteinase-activated Receptors

Scott R. Macfarlane, Michael J. Seatter, Toru Kanke et al. · 2006 · 1.1K citations

Potent and selective inhibition of nitric oxide-sensitive guanylyl cyclase by 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one.

John Garthwaite, Eric Southam, Caroline L. Boulton et al. · Molecular Pharmacology · 1995 · 1.1K citations

K+ is an endothelium-derived hyperpolarizing factor in rat arteries

G. Edwards, Kim A. Dora, M J Gardener et al. · Nature · 1998 · 1.1K citations

, , +10