The sulfonylurea receptor Sur is dispensable for chitin synthesis in <i>Drosophila melanogaster</i> embryos

Abstract

The data obtained suggest that there must exist another sulfonylurea-sensitive ABC transporter that either instead of Sur is the true sulfonylurea-sensitive transporter involved in chitin synthesis or is able to substitute Sur function during cuticle formation. Identification and characterisation of this factor is pivotal for understanding the mode of action of sulfonylurea as insecticide.