The effect of pulsed electrical fields on biological cells

Abstract

Experimental studies on the effect of pulsed electric fields on aquatic organisms and on cancer cells have shown that the stress level of micro- and macro-organisms can be controlled by varying the pulse amplitude and pulse duration. It could also be shown that an increase in frequency, or reduction in pulse duration, respectively, causes the location of the cell damage to change from the outer membrane to the nucleus. The experimental results can be explained by considering the equivalent circuit of biological cells.