Inclusion of human immunodeficiency virus Type 2 (HIV‐2) in a multiplex transcription‐mediated amplification assay does not affect detection of HIV‐1 and hepatitis B and C virus genotypes: a multicenter performance evaluation study

Abstract

The change in the oligonucleotide design of the Ultrio Elite assay to enable HIV-2 detection has not affected the analytical sensitivity for the other viruses regardless of the genotype. Genotype reference panels are instrumental to compare the sensitivity of nucleic acid test assay versions and could serve as an alternative to seroconversion panels.