Effect of intrafusal muscle mechanics on mammalian muscle spindle sensitivity

Abstract

Sensitivity differences between primary and secondary endings of mammalian muscle spindles under various conditions of stretch and fusimotor activation may be due to differences in their respective mechanoelectric transducers or to mechanical properties of the intrafusal muscle supporting those endings. This study of isolated cat muscle spindles examines the strain in individual intrafusal muscle fibers resulting from stretch and fusimotor stimulation. The degree of local stretch occurring at the sensory endings under these conditions was measured. The results support the hypothesis that the sensitivities of primary and secondary endings are quite similar. They are directly related to the local stretch of the underlying muscle which may be altered by changes in muscle stress and stiffness.