The programmed death 1/programmed death ligand 1 inhibitory pathway is up‐regulated in rheumatoid synovium and regulates peripheral T cell responses in human and murine arthritis - Concepedia

Concepedia

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The programmed death 1/programmed death ligand 1 inhibitory pathway is up‐regulated in rheumatoid synovium and regulates peripheral T cell responses in human and murine arthritis

197

Citations

38

References

2010

Year

Amalia Raptopoulou, George Βertsias, Dimitrios Makrygiannakis, Panagiotis Verginis, Iraklis Kritikos, Maria Tzardi, Lars Klareskog, Anca I. Catrina, Prodromos Sidiropoulos, Dimitrios T. Boumpas

Arthritis & Rheumatism

Abstract

The negative costimulatory PD-1/PDL-1 pathway regulates peripheral T cell responses in both human and murine RA. PD-1/PDL-1 in rheumatoid synovium may represent an additional target for immunomodulatory therapy in RA.

References

	Year	Citations

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