Expression of pituitary tumour‐derived, N‐terminally truncated isoform of fibroblast growth factor receptor 4 (ptd‐FGFR4) correlates with tumour invasiveness but not with G‐protein alpha subunit (<i>gsp</i>) mutation in human GH‐secreting pituitary adenomas

Abstract

We found that ptd-FGFR4 expression and gsp mutations occur independently of each other, and that ptd-FGFR4 expression is associated with more invasive tumours in patients with GH-secreting pituitary adenomas.