The constituents of Schizandra chinensis Baill. XII. Isolation and structure of a new lignan, gomisin R, the absolute structure of wuweizisu C and isolation of schisantherin D.

Abstract

A new dibenzocyclooctadiene lignan, gomisin R (4), was isolated from the fruits of Schizandra chinensis BAILL. (Schizandraceae) together with wuweizisu C (1)2) and schisantherin D (12).3) The absolute structure of 1, the relative structure of which has been elucidated by Liu et al., was defined by chemical correlation with dimethylgomisin J (2). The absolute structure of 4 was determined by spectral studies and chemical correlation with 1.