Concepedia

Preparation and evaluation of Cremophor-free paclitaxel solid dispersion by a supercritical antisolvent process

Jae‐Hyun Park, Yi-Dong Yan, Sang‐Cheol Chi, Doo Hyung Hwang, Srinivasan Shanmugam, Won Seok Lyoo, Jong Soo Woo, Chul Soon Yong, Han-Gon Choi

Journal of Pharmacy and Pharmacology · 2011 · 19 citations · 25 references

DOI

Abstract

Nano-scale paclitaxel solid dispersion without Cremophor EL provided advantageous results over Taxol with respect to the physicochemical properties, safety, clinic convenience and pharmacokinetic behaviour in rats.

References

25

Particle design using supercritical fluids: Literature and patent survey

Jennifer Jung, M. Perrut · The Journal of Supercritical Fluids · 2001 · 1.1K citations

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The current status of solid dispersions.

Ford Jl · PubMed · 1986 · 475 citations

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Camptothecin and taxol: discovery to clinic--thirteenth Bruce F. Cain Memorial Award Lecture.

Monroe E. Wall, Mansukh C. Wani · PubMed · 1995 · 373 citations

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Preparation and in vitro characterization of a eutectic based semisolid self-nanoemulsified drug delivery system (SNEDDS) of ubiquinone: mechanism and progress of emulsion formation

Sami Nazzal, Ivan I. Smalyukh, Oleg D. Lavrentovich et al. · International Journal of Pharmaceutics · 2002 · 270 citations

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Preparation, characterization and in vitro cytotoxicity of paclitaxel-loaded sterically stabilized solid lipid nanoparticles

Mi-Kyung Lee, Soo‐Jeong Lim, Chong‐Kook Kim · Biomaterials · 2007 · 240 citations

, , +8