Elevated levels of oxidative DNA damage in lymphocytes from patients with Alzheimer’s disease11Abbreviations used: AD, Alzheimer’s disease; Endo III, Endonuclease III; 8OHA, 8-hydroxyadenine; 8OHG, 8-hydroxyguanine; 8OHdG, 8-hydroxy-2′-deoxyguanosine; Fapy-Ade, 4,6-diamino-5-formamidopyrimidine; Fapy-Gua, 2,6,-diamino-4-hydroxy-5-formamidopyrimidine; Fpg, formamidopyrimidine glycosilase; H2O2, hydrogen-peroxide; .OH, hydroxyl radical; PBS, phosphate-buffered saline; ROS, reactive oxygen species; RT, room temperature; SSB, single strand break

Neurobiology of Aging · 2002 · 105 citations · 40 references