Differences in human and porcine platelet oligosaccharides may influence phagocytosis by liver sinusoidal cells in vitro

Abstract

Differences between human and porcine ASGR1 and Mac-1, in combination with a significantly higher number of galactose and N-acetyl glucosamine-containing oligosaccharides on human platelets contribute, in part, to platelet loss seen in porcine liver xenotransplantation.