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Immune recovery vitritis presenting as panuveitis following therapy with protease inhibitors.
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2000
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Protease InhibitorsPrimary ImmunodeficiencyViral PersistenceAutoimmune DiseaseVasculitisAcquired Immunodeficiency SyndromeHuman RetrovirusInactive Cmv RetinitisImmunologyAntiviral ResponseVirologyAutoimmunityImmunologic DiseaseChronic Viral InfectionHivImmunotherapyMedicine
Immune reconstitution in acquired immunodeficiency syndrome (AIDS) patients on highly active anti-retroviral therapy (HAART) with cytomegalovirus (CMV) retinitis manifested as posterior segment intraocular inflammation has been reported. We report an adult HIV-positive Indian male with clinically inactive CMV retinitis who developed panuveitis with hypopyon. This was related to immune recovery mediated by combination anti-retroviral treatment, including protease inhibitors.