Association of a Mutation in <i>LACC1</i> With a Monogenic Form of Systemic Juvenile Idiopathic Arthritis

Abstract

Our findings provide strong genetic evidence of an association of a mutation in LACC1 with systemic JIA in the families studied. Association of LACC1 with Crohn's disease and leprosy has been reported and justifies investigation of its role in autoinflammatory disorders.