Concepedia

Stem cell marker CD271 is expressed by vasculogenic mimicry-forming uveal melanoma cells in three-dimensional cultures.

Klara Valyi‐Nagy, Bernadett Kormos, Mohamed M. Ali, Deepak Shukla, Tibor Vályi-Nagy

PubMed · 2012 · 39 citations · 20 references

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Abstract

These findings suggest that VM-forming uveal melanoma cells acquire a cancer stem cell-like phenotype that may play a role in the increased therapy resistance of these cells.

References

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Vascular Channel Formation by Human Melanoma Cells in Vivo and in Vitro: Vasculogenic Mimicry

Andrew J. Maniotis, Robert Folberg, Angela R. Hess et al. · American Journal Of Pathology · 1999 · 2.1K citations · Full text

, , +14

A Tumorigenic Subpopulation with Stem Cell Properties in Melanomas

Dong Fang, Thiennga K. Nguyen, Kim Leishear et al. · Cancer Research · 2005 · 1.3K citations · Full text

Human melanoma-initiating cells express neural crest nerve growth factor receptor CD271

Alexander D. Boiko, Olga V. Razorenova, Matt van de Rijn et al. · Nature · 2010 · 712 citations · Full text

, , +9

The Prognostic Value of Tumor Blood Vessel Morphology in Primary Uveal Melanoma

Robert Folberg, Volker Rummelt, R. Parys-Van Ginderdeuren et al. · Ophthalmology · 1993 · 422 citations

, , +7

Human CD271-Positive Melanoma Stem Cells Associated with Metastasis Establish Tumor Heterogeneity and Long-term Growth

Gianluca Civenni, Anne Walter, Nikita Kobert et al. · Cancer Research · 2011 · 324 citations · Full text