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[Frequency of the APOE-4 allele in Alzheimer's disease and its variation with age in Asturias (Spain)].
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1999
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In Asturias, APOE genotyping can not be used for the presimptomatic diagnosis of Alzheimer's disease. However, individuals carrying this allele would have a higher probability of developing the disease at an age between 65 and 80 years if they are predisposed (genetically and/or environmentally) to the disease.