Pituitary Peptides

Abstract

Abstract An examination of fractions from extracts of porcine pituitary has revealed the presence of a number of peptide components active in restoring the ability of hypophysectomized rats to acquire a conditioned avoidance response. None of the products appears to exhibit hormonal activity as measured by effects on adrenal, testis, thymus, or total body weight. The active component of lowest molecular weight was isolated and characterized as deglycinamide9-lysine vasopressin.