Methylglyoxal‐augmented manuka honey as a topical anti–<i>Staphylococcus aureus</i> biofilm agent: safety and efficacy in an in vivo model

Abstract

Sinus irrigation with MH/MGO at MGO concentrations between 0.9 and 1.8 mg/mL is both safe to mucosa and efficacious against S. aureus biofilm. MH/MGO irrigation could represent a viable treatment option for recalcitrant CRS.