A retroviral wild-type p53 expression vector penetrates human lung cancer spheroids and inhibits growth by inducing apoptosis

Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation.

Yael Gavrieli, Yoav Sherman, Shmuel A. Ben‐Sasson · The Journal of Cell Biology · 1992 · 9.5K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +13

Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6

Elisheva Yonish-Rouach, Dalia Resnftzky, Joseph Lotem et al. · Nature · 1991 · 2.1K citations

Medicine, Hematology, Oncology +13

Improved retroviral vectors for gene transfer and expression.

A. Dusty Miller, G J Rosman · PubMed · 1989 · 2K citations

Life Sciences, Biotechnology, Molecular Biology +16

In Vivo Gene Transfer with Retroviral Vector-Producer Cells for Treatment of Experimental Brain Tumors

Kenneth W. Culver, Zvi Ram, Stuart Wallbridge et al. · Science · 1992 · 1.5K citations

Medicine, Cancer Biology, Oncology +17

p53: A Frequent Target for Genetic Abnormalities in Lung Cancer

Takashi Takahashi, Marion M. Nau, Itsuo Chiba et al. · Science · 1989 · 1.2K citations

Medicine, Genetics, Molecular Genetics +15