Thiol/disulfide homeostasis: A prognostic biomarker for patients with advanced non-small cell lung cancer?

Abstract

These results suggest that in advanced stage NSCLC, the native thiol, total thiol, and disulfide levels decrease, while the native thiol/disulfide ratio does not change. Low levels of thiol/disulfide parameters are related to tumor aggressiveness and may predict a poor outcome for patients with NSCLC.