Concepedia

Therapeutic antibody fragments with prolonged in vivo half-lives

Andrew P. Chapman, Pari Antoniw, Mariangela Spitali, Shauna West, Sue Stephens, David King

Nature Biotechnology · 1999 · 348 citations · 12 references

DOI

Concepts

References

12

Randomised double-blind comparison of chimeric monoclonal antibody to tumour necrosis factor α (cA2) versus placebo in rheumatoid arthritis

Michael J. Elliott, Ravinder N. Maini, Marc Feldmann et al. · The Lancet · 1994 · 1.7K citations

, , +15

Assembly of a Functional Immunoglobulin F <sub>v</sub> Fragment in <i>Escherichia coli</i>

Arne Skerra, Andreas Plückthun · Science · 1988 · 969 citations

, , +17

High-Level Expression of a Recombinant Antibody from Myeloma Cells Using a Glutamine Synthetase Gene as an Amplifiable Selectable Marker

C. R. Bebbington, G. Renner, Scott Thomson et al. · Nature Biotechnology · 1992 · 465 citations

, , +16

High Level Escherichia coli Expression and Production of a Bivalent Humanized Antibody Fragment

Paul Carter, Robert F. Kelley, Maria Luı́sa Rodrigues et al. · Nature Biotechnology · 1992 · 330 citations

, , +14

A humanized monoclonal antibody produced in transgenic plants for immunoprotection of the vagina against genital herpes

Larry Zeitlin, Stuart S. Olmsted, Thomas R. Moench et al. · Nature Biotechnology · 1998 · 283 citations

, , +11