Clinical significance of positive cranial bone flap cultures and associated risk of surgical site infection after craniotomies or craniectomies

Abstract

Operative factors such as the way the skin is prepared before the incision rather than the skin flora contaminants on the bone flaps may play an important role in the pathogenesis of SSIs after craniotomy/craniectomy. Gliadel wafers significantly increased the risk of SSI after procedures to treat tumors.