Mannose-binding lectin gene-2 polymorphisms and serum mannose-binding lectin levels in Behçet's disease.

Abstract

The frequencies of the four MBL2 genetic polymorphisms examined were not different in BD patients and healthy controls. However, the presence of genital ulcer, eye involvement, and neuro-Behcet's disease were found to be associated with MBL2 polymorphisms that are associated with the production of high levels of MBL or functional MBL.