Thrombocytopenia in the experimental leptospirosis of guinea pig is not related to disseminated intravascular coagulation

Abstract

Pathologic and hematological studies for experimental leptospirosis of guinea pig indicated that the thrombocytopenia found in guinea pigs did not correlate with the occurrence of DIC. The platelet aggregation and Kupffer cells phagocytosis might be the potential causes of thrombocytopenia in severe leptospirosis.