Polyphosphate Ester as a Synthetic Agent. VI. The Bischler-Napieralski Reaction of Tryptamine and Tryptophan Derivatives by Means of Polyphosphate Ester

Abstract

Polyphosphate ester (PPE) was shown to be a good agent of the Bischler-Napieralski reaction for the synthesis of 3, 4-dihydro-β-carboline derivatives. 3, 4-Dihydro-β-carboline-3-carboxylic acid system, a key intermediate in the cyclization of acyltryptophan series, could be isolated and characterized by this procedure.