Properties of collagen and hyaluronic acid composite materials and their modification by chemical crosslinking

Abstract

This article describes properties of composites of collagen-hyaluronic acid shaped to layered materials. According to the results, interactions of these two polymers are very strong. The properties can be influenced by chemical crosslinking using glyoxal and starch dialdehyde. The different behavior during enzymatic degradation by collagenase and in swelling experiments is discussed in relation to material composition. The valuable properties of the composites observed in this study show the possibility of their use as biomaterials.