Abolition of herpes simplex cytopathic effect after treatment with peroxidase generated hypothiocyanite.

Abstract

HSV1 suspensions were pre-incubated in a lactoperoxidase thiocyanate oxidizing system before inoculation in MRC5 fibroblast cultures. This pre-treatment could either delay or even abolish the HSV1 cytopathic potentiality. The effect was found to be time-dependent.