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A randomized trial comparing the dorzolamide-timolol combination given twice daily to monotherapy with timolol and dorzolamide11Ms. Boyle, Dr. Ghosh, and Dr. Adamsons were employees of Merck & Co., Inc, the manufacturer of timolol and dorzolamide, at the time this study was conducted. COSOPT and TRUSOPT are trademark products of Merck & Co., Inc, Whitehouse Station, New Jersey. The other authors have no proprietary interest in timolol, dorzolamide, or Merck.

Medicinal ChemistryClinical TherapeuticMedicineMetronomic TherapyDorzolamide-timolol CombinationClinical TrialsPharmacotherapyRandomized TrialDrug TrialPharmacologyNew JerseyDrug Discovery