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TORULA HISTOLYTICA (CRYPTOCOCCUS HOMINIS) MENINGITIS: CASE REPORT AND THERAPEUTIC EXPERIMENTS

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Case Reports1 May 1945TORULA HISTOLYTICA (CRYPTOCOCCUS HOMINIS) MENINGITIS: CASE REPORT AND THERAPEUTIC EXPERIMENTSSTEWART H. JONES, M.D., GUSTAVUS H. KLINCK JR., M.D.STEWART H. JONES, M.D., GUSTAVUS H. KLINCK JR., M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-22-5-736 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptApproximately 80 cases ofTorula histolyticameningitis have been reported since 1861, when, according to Freeman,1Zenker recorded what was probably the first case. Less than half of the cases have been recognized before death.2It has been mistaken for tuberculous meningitis, brain abscess, brain tumor, encephalitis, lymphocytic choriomeningitis, and dementia paralytica.Torula histolyticais widely distributed in nature, having been isolated from wasp nests, stems of grasses and plants, bodies of insects, canned butter and milk.3, 4Lesions such as localized dorsolumbar abscess,5pelvic and inguinal abscess,6and nasopharyngeal ulcers7have been caused byTorula histolytica. Some8, 9are...Bibliography1. FREEMAN W: Torula infection of the central nervous system, Jr. f. Psychol. u. Neurol., 1931, xliii, 236. Google Scholar2. LEVIN EA: Torula infection of the central nervous system, Arch. Int. Med., 1937, lix, 667-684. CrossrefGoogle Scholar3. JACOBSENSCHAMBERGMORROW HPJFH: Fungous disease, 1932, Chas. C. Thomas, Baltimore, p. 253. Google Scholar4. KLEIN E: Pathogenic microbes in milk, Jr. Hyg., 1901, i, 78-95. CrossrefGoogle Scholar5. BREWERWOOD GEFC: Blastomycosis of the spine; double lesion; two operations; recovery, Ann. Surg., 1908, xlviii, 889-896. CrossrefGoogle Scholar6. MCGEHEEMICHELSON JLID: Torula infection in man, Surg., Gynec. and Obst., 1926, xlii, 803-808. Google Scholar7. GILL WD: Torula mycosis in man with special reference to involvement of the upper respiratory tract, with case reports, Trans. Am. Laryngol., Rhinol., and Otol. Soc., 1934, xl, 247-262. Google Scholar8. RAPPAPORTKAPLAN BZB: Generalized torula mycosis, Arch. Path., 1926, i, 720-741. Google Scholar9. STODDARDCUTLER JLEC: Torula infection in man, Monograph No. 6, Rockefeller Inst. for Med. Research, 1916. Google Scholar10. HOFF CL: Immunity studies of Cryptococcus hominis (Torula histolytica) in mice, Jr. Lab. and Clin. Med., 1942, xxvii, 751-754. Google Scholar11. SHAPIRONEAL LLJB: Torula meningitis, Arch. Neurol. and Psychiat., 1925, xiii, 174-190. CrossrefGoogle Scholar12. MARSHALLTEED MRW: Torula histolytica meningo-encephalitis; recovery following bilateral mastoidectomy and sulfonamide therapy; preliminary report, Jr. Am. Med. Assoc., 1942, cxx, 527-529. CrossrefGoogle Scholar13. Queries and minor notes, Jr. Am. Med. Assoc., 1938, cx, 231. Google Scholar14. GOMEZ-VEGA P: Mycostatic studies on certain moniliae and related fungi, Arch. Dermat. and Syph., 1935, xxxii, 49-58. CrossrefGoogle Scholar15. MYERS HB: Thymol therapy in actinomycosis, Jr. Am. Med. Assoc., 1937, cviii, 1875. CrossrefGoogle Scholar16. WARVIRAWSON WNRW: Torula meningitis, Arch. Int. Med., 1942, lxix, 90-98. CrossrefGoogle Scholar17. KOLMERTUFT JAL: Clinical immunology, 1941, W. B. Saunders Co., Philadelphia, 1st ed., p. 284. Google Scholar18. BODANSKY O: Reduction of toxicity of 2-sulfanilamidopyrimidine (sulfadiazine) by phenylazo-alpha-alpha-diaminopyridine hydrochloride (pyridium) in the mouse, Proc. Soc. Exper. Biol. and Med., 1942, xlix, 216-218. CrossrefGoogle Scholar19. FEINSTONE WH: The toxicity, absorption, and chemotherapeutic activity of 2-sulfanilamidopyrimidine (sulfadiazine), Bull. Johns Hopkins Hosp., 1940, lxvii, 427-456. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Troy, New York*Received for publication December 10, 1943.From the Departments of Medicine and Pathology of the Samaritan Hospital, Troy, N. Y.†Present address, Lahey Clinic, Boston, Massachusetts. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byChronic mycotic meningitis with spinal involvement (arachnoiditis): A report of five casesCryptococcosisCryptococcosisTREATMENT OF CENTRAL NERVOUS SYSTEM CRYPTOCOCCOSIS: A REVIEW AND REPORT OF FOUR CASES TREATED WITH ACTIDIONE*CHARLES A. CARTON, M.D.Blastomicose do sistema nervosoTORULA HISTOLYTICA MENINGO-ENCEPHALITIS: FURTHER REPORT*MARK MARSHALL, M.D., F.A.C.P., R. WALLACE TEED, M.D.Torula Granuloma of the Cervical Spinal CordCryptococcosisTORULOSIS OF THE CENTRAL NERVOUS SYSTEM: REVIEW OF LITERATURE AND REPORT OF FIVE CASES*WILLIAM H. MOSBERG JR., M.D., JAMES G. ARNOLD JR., M.D.Cutaneous Cryptococcosis**From the Division of Dermatology, University of Minnesota, H. E. Michelson, M.D., Director.TORULOSIS OF THE CENTRAL NERVOUS SYSTEMFungus diseases encountered in general hospital practice 1 May 1945Volume 22, Issue 5Page: 736-745KeywordsAbscessesBrainDementiaEncephalitisHospital medicineLesionsMeningitisUlcers ePublished: 1 December 2008 Issue Published: 1 May 1945 PDF downloadLoading ...

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