PubMed · 1990 · 45 citations · 3 references
Veterinary MedicinePoultry ScienceVeterinary PathologyHepatologyPoultry MedicinePoultry PathologyBacterial Diseases Of PoultryBird DiseasesHistopathology Of PoultryPoultry Gastrointestinal DiseasesPoultry Infectious DiseasesPoultry NecropsyBroiler ChickensCardiac LesionsClostridium PerfringensClostridium Perfringens InfectionHepatic InvolvementPoultry Disease SyndromesPoultry Necropsy FindingsPoultry Organ Pathology
A detailed descriptive study was done on broiler chickens with abnormal livers found at processing. Two syndromes were evident: those birds with enlarged, pale, firm livers, designated hepatosis, with Clostridium perfringens type A often isolated; and ascitic birds with cobblestone-appearing livers. Livers with hepatosis had marked proliferation of bile ducts; ascitic livers had normal architecture. Hearts from birds with ascites had elevated right ventricular/total ventricular weight ratios, whereas hearts from normal birds and birds with hepatosis did not. Two isolates of C. perfringens produced necrotic enteritis in experimental birds; an attempt to reproduce hepatosis with these isolates was unsuccessful.
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