Polyadenylic Acid Sequences in Yeast Messenger Ribonucleic Acid

Abstract

Polyadenylate sequences are found covalently linked to yeast mRNA molecules.The poly(A) sequences are relatively homogeneous in size and have an average chain length of about 50 residues.They are located at the 3' end of the mRNA molecule.Our data suggest that some mRNA molecules may not contain poly(A) sequences and that no poly(A) sequences are present in rRNA.The occurrence of poly(A) sequences in the mRNA molecules of mammals and yeast suggests that this may be a general feature of eucaryotic organisms.