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Site-directed mutagenesis studies of the NADPH-binding domain of rat steroid 5α-reductase (isozyme-1) I: Analysis of aromatic and hydroxylated amino acid residues111Abbreviations: NADP+, Nicotinamide adenine dinucleotide phosphate; NADPH, Reduced NADP+; r5αR-1, Rat steroid 5α-reductase (isozyme-1); [3H]-T, [3H]-testosterone; [3H]-DHT, [3H]-5-dihydrotestosterone.

Molecular PharmacologyBiochemistryMedicineNatural SciencesAmino Acid Residues111abbreviationsBiochemical GeneticsMolecular BiologyAromataseEndocrinologyNadph-binding DomainMetabolismPharmacologyReduced Nadp+Redox BiologySteroid Metabolism