Caveolin‐1 expression regulates blood–retinal barrier permeability and retinal neovascularization in oxygen‐induced retinopathy

Abstract

Caveolin-1 may play an important role in induction of retinal neovascularization. SiRNA against caveolin-1 can inhibit experimental retinal hyperpermeability and neovascularization. Therefore, the inhibition of caveolin-1 may be a powerful and novel therapeutic tool for the treatment of ischaemia-induced retinal diseases.