Comparison of immunofluorescence with commercial monoclonal antibodies to biochemical and biological techniques for typing clinical herpes simplex virus isolates

Abstract

Immunofluorescence with monoclonal antibody reagents from two commercial sources for differentiating herpes simplex viruses types 1 and 2 demonstrated 100% agreement with cell culture selectivity (chicken embryo and guinea pig embryo cells) and (E)-5-(2-bromovinyl)-2'-deoxyuridine sensitivity for typing a total of 94 clinical herpes simplex virus isolates.