Differences in Brain Structure and Function in Older Adults with Self-Reported Disabling and Nondisabling Chronic Low Back Pain

Abstract

Brain structure and function is different in older adults with disabling CLBP compared with those with nondisabling CLBP. Deficits in brain morphology combining groups are associated with pain duration and poor physical function. Our findings suggest brain structure and function may play a key role in chronic pain related disability and may be important treatment targets.