ANTIMETABOLITES PRODUCED BY MICROORGANISMS. X

Abstract

L-2-Amino-4-(2-aminoethoxy)-trans-3-butenoic acid was isolated from a fermentation broth of an unidentified species of Streptomyces, X-11, 085. This substance inhibited the growth of Streptomyces cellulosae in a chemically defined minimal medium. The growth inhibition was reversed noncompetitively by L-cysteine and competitively by L-lysine, L-arginine and L-ornithine.