The new <scp>KCNQ2</scp> activator 4‐<scp>C</scp>hlor‐<scp>N</scp>‐(6‐chlor‐pyridin‐3‐yl)‐benzamid displays anticonvulsant potential

Abstract

Our data indicate that 4-Chlor-N-(6-chlor-pyridin-3-yl)-benzamid is a potent KCNQ activator with a selectivity for KCNQ2 containing channels. It strongly reduces neuronal excitability and displays anticonvulsant activity in vivo.