Journal of Biological Chemistry · 1973 · 77 citations · 22 references
Life SciencesMicrobiologyMolecular BiologyNucleic Acid BiochemistryRna BiologyRna ProcessingNucleotide MetabolismRibosomal Rna ProcessingRibosome BiogenesisRna CleavageRna ModificationTranslation In ProkaryotesCleavageDouble-stranded Rna CleavagePre-ribosomal Rna CleavagePrecursor Ribosomal Rna CleavageRibonuclease Iii CleavageRibosomal Rna Processing In BacteriaRibosomal RnasRrna Modification
Abstract AB105, a strain deficient in RNase III, produces a 30 S precursor to ribosomal RNA (mol wt, 2.1 x 106) that is then metabolized to 25 and 17.5 S rRNA; after infection of the strain with T7 phage, a precursor of T7 messenger RNA of molecular weight 3.5 x 106 is formed and then metabolized to smaller mRNA chains. Purified RNase III cleaves the extracted large RNAs to products with the electrophoretic mobilities of the cleavage products produced in vivo.
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Ribonucleoprotein particles from Escherichia coli
A. Tissières, James D. Watson, David Schlessinger et al. · Journal of Molecular Biology · 1959 · 694 citations
Polyadenylic Acid Sequences: Role in Conversion of Nuclear RNA into Messenger RNA
James Darnell, Lennart Philipson, Randolph Wall et al. · Science · 1971 · 567 citations