Induction of an Inflammatory and Prodegradative Phenotype in Autologous Fibroblast‐like Synoviocytes by the Infrapatellar Fat Pad From Patients With Knee Osteoarthritis

Abstract

This study showed that the IFP has a potential role in the induction of synovial inflammation in patients with severe knee OA. Furthermore, secretion of PGE2 by the IFP may be involved in the OA inflammatory process.